A Randomized Study Comparing the Efficacy of Three Hepatitis B Vaccine Induction Regimens in Adult Patients with Hematological Malignancies

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ÖZKURT Z. N., Suyani E., Haznedar R., Yagci M.

TURKISH JOURNAL OF HEMATOLOGY, cilt.33, sa.3, ss.231-235, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4274/tjh.2015.0079
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.231-235
  • Anahtar Kelimeler: Hepatitis B, Vaccine, Hematological malignancies, ACUTE LYMPHOBLASTIC-LEUKEMIA, VIRUS VACCINATION, REACTIVATION, INFECTION, CHILDREN
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: Non-responsiveness to hepatitis B virus (HBV) vaccines is not rare in hemato-oncological patients due to disease-associated or treatment-induced immune suppression. Although different strategies have been employed to improve the response rates, to date there is not an approved schedule for HBV immunization in patients with hematological malignancies. We designed a prospective randomized study to evaluate the efficacy of 3 different induction regimens for HBV vaccination.