Multicenter analytical performance evaluation of a fully automated anti-Mullerian hormone assay and reference interval determination

Anckaert E., Oktem M. , Thies A., Cohen-Bacrie M., Daan N. M. P. , Schiettecatte J., ...More

CLINICAL BIOCHEMISTRY, vol.49, no.3, pp.260-267, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.1016/j.clinbiochem.2015.10.008
  • Title of Journal : CLINICAL BIOCHEMISTRY
  • Page Numbers: pp.260-267


Objectives: Anti-Mullerian hormone (AMH) is an established biomarker for assessing ovarian reserve and predicting response to controlled ovarian stimulation. Its routine clinical use is hampered by the variability and low-throughput of available enzyme-linked immunosorbent assays (ELISA). The presented study examined if a fully automated AMH electrochemiluminescence assay (ECLIA; Elecsys (R) AMH assay, Roche Diagnostics) was suitable for measuring AMH levels in healthy women and in those diagnosed with polycystic ovary syndrome (PCOS).