Multicenter analytical performance evaluation of a fully automated anti-Mullerian hormone assay and reference interval determination

Anckaert, E.; Oktem, RIDVAN; Thies, A.; Cohen-Bacrie, M.; Daan, N.; Schiettecatte, J.; Mueller, C.; Topcu, D.; Groening, A.; Ternaux, F.; Engel, C.; Engelmann, S.; Milczynski, C.

doi:10.1016/j.clinbiochem.2015.10.008

Multicenter analytical performance evaluation of a fully automated anti-Mullerian hormone assay and reference interval determination

Anckaert E., Oktem M., Thies A., Cohen-Bacrie M., Daan N. M. P., Schiettecatte J., ...Daha Fazla

CLINICAL BIOCHEMISTRY, cilt.49, sa.3, ss.260-267, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 49 Sayı: 3
Basım Tarihi: 2016
Doi Numarası: 10.1016/j.clinbiochem.2015.10.008
Dergi Adı: CLINICAL BIOCHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.260-267
Anahtar Kelimeler: Immunoassay, Anti-Mullerian hormone (AMH), Electrochemiluminescence immunoassay (ECLIA), Polycystic ovary syndrome (PCOS), Elecsys (R) AMH, POLYCYSTIC-OVARY-SYNDROME, MLLERIAN HORMONE, SYNDROME PCOS, MOUSE OVARY, IN-VITRO, GEN II, DEFINITION, WOMEN, REPRODUCIBILITY, IMMUNOASSAY
Gazi Üniversitesi Adresli: Hayır

Özet

Objectives: Anti-Mullerian hormone (AMH) is an established biomarker for assessing ovarian reserve and predicting response to controlled ovarian stimulation. Its routine clinical use is hampered by the variability and low-throughput of available enzyme-linked immunosorbent assays (ELISA). The presented study examined if a fully automated AMH electrochemiluminescence assay (ECLIA; Elecsys (R) AMH assay, Roche Diagnostics) was suitable for measuring AMH levels in healthy women and in those diagnosed with polycystic ovary syndrome (PCOS).