The effect of hypothyroidism, hyperthyroidism, and their treatment on parameters of oxidative stress and antioxidant status

Erdamar H., Demirci H., Yaman H., Erbil M. K., Yakar T., Sancak B., ...More

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, vol.46, no.7, pp.1004-1010, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 7
  • Publication Date: 2008
  • Doi Number: 10.1515/cclm.2008.183
  • Journal Name: CLINICAL CHEMISTRY AND LABORATORY MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1004-1010
  • Keywords: antioxidant status, hyperthyroidism, hypothyroidism, oxidative stress, FREE-RADICAL SCAVENGERS, LIPID-PEROXIDATION, GRAVES-DISEASE, RAT, MECHANISM, OXIDANTS, TISSUE, PROPYLTHIOURACIL, MEDIATORS, CATALASE
  • Gazi University Affiliated: Yes

Abstract

Background: Free radical-mediated oxidative stress has been implicated in the etiopathogenesis of several autoimmune disorders. Also, there is growing evidence supporting the role of reactive oxygen species in the pathogenesis of thyroid disorders. The aim of this study was to investigate the influence of hypothyroidism, hyperthyroidism, and their treatments on the metabolic state of oxidative stress, and antioxidant status markers.