Evaluation of intraprostatic metabolism of 1,25-dihydroxyvitamin D-3 (calcitriol) using a microdialysis technique

Konety B., Somogyi G., Atan A., Muindi J., Chancellor M., Getzenberg R.

UROLOGY, cilt.59, sa.6, ss.947-952, 2002 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 59 Sayı: 6
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1016/s0090-4295(01)01652-1
  • Dergi Adı: UROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.947-952
  • Gazi Üniversitesi Adresli: Hayır

Özet

Objectives. 1,25-dihydroxyvitamin D-3 (calcitriol) inhibits prostate cancer growth in vitro and in vivo. We used a prostate microdialysis technique to better understand the intraprostatic pharmacokinetics of calcitriol, which in turn would facilitate planning for systemic calcitriol therapy in patients with prostate cancer.