BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.117, no.12, pp.722-725, 2016 (SCI-Expanded)
Article / Article
BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
Science Citation Index Expanded (SCI-EXPANDED), Scopus
ischemia reperfusion, erythrocyte deformability, intravenous ibuprofen, lornoxicam, rat, RED-BLOOD-CELL, SKELETAL-MUSCLE, FLOW, LUNG
Gazi University Affiliated:
BACKGROUNDAND AIM: Acute hind limb ischemia reperfusion (I/R) injury is a common consequence of abdominal aorta cross-clamping during aortic surgery. Erythrocyte deformability is affected by I/R process and may lead to increased tissue and organ injury. Lornoxicam and intravenous ibuprofen are becoming commonly used as non-steroidal anti-inflammatory drugs (NSAID) for postoperative analgesia. In this study, we aimed to investigate the effects of lornoxicam (2 mg/kg iv) and intravenous ibuprofen (30 mg/kg iv) on erythrocyte deformability in I/R model in rats.