Surgical treatment in patients with non-small cell lung cancer with vertebral invasion is controversial. Current studies have shown that, the multimodal therapy (induction chemo-radiotherapy, surgery) has acceptable morbidity and mortality in selected patients. There is no common consensus for performing surgery after curative intent chemoradiotherapy. Here we presented a multimodal therapy for a patient with pancoast tumor invading vertebrae. A 51-year-old male patient has a 10x7 cm, non-small cell lung cancer diagnosed lesion in the apical of left lung with pathological involvement in PET / CT. After curative-intent chemo-radiotherapy, the patient underwent enblock left 1-3rd rib resection, 4th rib partial resection with left upper lobectomy and mediastinal lymph node dissection, C7 partial excision and T1-3 hemivertebrectomy as a salvage surgery. No complication was observed in the postoperative period.