Akademik Veri Yönetim Sistemi
SAUDI MEDICAL JOURNAL, cilt.29, sa.12, ss.1719-1722, 2008 (SCI-Expanded)
Objectives: To investigate intra cuff pressure changes in low-flow anesthesia (LFA) and high-flow (HFA) N(2)O anesthesia during moderate-duration surgical procedures. Methods: We carried out this prospective, randomized, single blind study at Numune Educational and Research Hospital, Ankara, Turkey between January to December 2005. Seventy patients aged between 18-65 years, American Society of Anesthesiologists (ASA) physical status grades I-III, undergoing elective surgery were enrolled in this study. Following a standardized induction, anesthesia was maintained with isoflurane (end-tidal 0.91%) at 4 L/minute for the HFA group, or 1 L/minute for the LFA group fresh gas flows. Endotracheal tube cuff (intra cuff) pressures were measured continuously with a pressure manometer, and inspired oxygen and N(2)O levels were noted every 10 minutes throughout the study. Results: There was no significant difference between HFA and LFA groups for initial (first) cuff pressures (mean +/- SD, HFA=20.9 +/- 4.19, LFA=20.4 +/- 4.1 1, cmH(2)O), and maximum cuff pressures (MCP) (mean +/- SD, HFA=32.3 +/- 18.74, LFA=33.5 +/- 8.89, cmH(2)O) (p>0.05). Me time to reach the maximum intra cuff pressure was significantly shorter in the LFA group (77.4 +/- 20.33 minutes), than the HFA group (89.3 +/- 23.94 minutes), (p=0.038). Between the tenth and nineteenth minutes, inspired oxygen level was significantly higher in the HFA group (p=0.001), whereas inspired N(2)O was significantly higher in the LFA group (p=0.001). Conclusion: The intra cuff pressures should be monitored carefully during LFA, since the duration to reach the maximum intra cuff pressures was shorter than that of HFA.