The Effect of Quetiapine on Treatment of Experimental Acute Spinal Cord Injury

AYTAR M. H., ÇİVİ S., KAYMAZ A. M., ERGUN S., KAYMAZ F. F., PASAOGLU A.

Turkish Neurosurgery, cilt.28, sa.1, ss.105-110, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.5137/1019-5149.jtn.17476-16.1
  • Dergi Adı: Turkish Neurosurgery
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.105-110
  • Gazi Üniversitesi Adresli: Evet

Özet

AIM: It is well known that treatment modalities against secondary damage due to spinal cord injury (SCI) are very important. This phase has been researched in many experimental studies. Apoptosis is one of the major mechanisms of secondary damage on spinal cord. The present study was undertaken to determine if quetiapine, a 5-HT2 receptor blocker atypical antipsychotic agent can rescue neuronal cells from apoptosis in a SCI model.