Evaluation of Erythrocyte Deformability in Experimentally Induced Osteoporosis in Male Rats and the Effects of Vitamin C Supplementation on Erythrocyte Deformability and Bone Mineral Density

ARSLAN, MUSTAFA; Comu, Faruk; KELEŞ, IŞIK; Arslan, Ayse

doi:10.4274/tftr.68725

Evaluation of Erythrocyte Deformability in Experimentally Induced Osteoporosis in Male Rats and the Effects of Vitamin C Supplementation on Erythrocyte Deformability and Bone Mineral Density

ARSLAN M., Comu F. M., KELEŞ I., Arslan A.

TURKIYE FIZIKSEL TIP VE REHABILITASYON DERGISI-TURKISH JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION, cilt.58, sa.2, ss.121-125, 2012 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 58 Sayı: 2
Basım Tarihi: 2012
Doi Numarası: 10.4274/tftr.68725
Dergi Adı: TURKIYE FIZIKSEL TIP VE REHABILITASYON DERGISI-TURKISH JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.121-125
Gazi Üniversitesi Adresli: Evet

Özet

Objective: Male osteoporosis (OP) is a major problem in clinical medicine, but has gained less interest than female OP The mechanisms of male OP have not been explained well and are not clear yet. It is suggested that there is a role for oxidative stress in the pathophysiology of many diseases, one of them being OR In this study, we investigated the effect of orchiectomy on bone mineral density (BMD), the level of antioxidant enzymes, lipid peroxidation, and erythrocyte deformability in rats and the effect of vitamin C supplementation on the possible changes in these parameters.