The crystal and molecular structure of two drug compounds: Tazettine and corydaldine


İDE S., Sener B., Temizer H., Konukol S.

CRYSTAL RESEARCH AND TECHNOLOGY, cilt.31, sa.5, ss.617-624, 1996 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 5
  • Basım Tarihi: 1996
  • Doi Numarası: 10.1002/crat.2170310515
  • Dergi Adı: CRYSTAL RESEARCH AND TECHNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.617-624
  • Gazi Üniversitesi Adresli: Hayır

Özet

The title compounds Tazettine (C18H21NO5) and Corydaldine (3,4-dihydro-6,7-dimethoxy-1(2H)-isoquinolinone, C11H13NO3) have been isolated from the bulbs of Pancratium maritimum L. (Amaryllidaceae) and Corydalis solida subspecies brachyloba, respectively. The X-ray structures were solved for Tazettine (I) and Corydaldine (II) (lambda MoKa, R = 0.0499 and 0.0418. respectively). Crystals of (I) are orthorhombic, a=7.115(1), b=13.377(1), c=16.878(1) Angstrom, Z=4, D-calc=1.370 g . cm(-3) space group P2(1)2(1)2(1). Crystals of (II) are monoclinic, a=10.641(1), b=6.636(1); c=14.938(1) Angstrom, beta=90.31(1)degrees: Z=4, D-calc=1.305 g . cm(-3), space group P2(1)/a.