Carbonic Anhydrase Isoenzymes I and II Inhibition Potentials of Leiotulus dasyanthus (K. Koch) Pimenov&Ostr. and Ferulago pauciradiata Boiss.&Heldr. (Apiaceae)

KARAKAYA S., Bingol Z., GÜLÇİN İ., Delimustafaoglu F., DUMAN H., KILIÇ C. S.

BEZMIALEM SCIENCE, vol.9, no.2, pp.153-157, 2021 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.14235/bas.galenos.2020.4127
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.153-157
  • Gazi University Affiliated: Yes


Objective: Members of the Apiaceae family have many biological and pharmacological effects like anticancer, antidiabetic, antioxidant, anti-inflammatory, anti-hypertensive, anticoagulant, antimicrobial, and anticholinesterase. Also, some of them are consumed as vegetables, pickles, and spices. Carbonic anhydrase has a remarkable role in diseases like osteoporosis, glaucoma, edema, cancer, epilepsy, and obesity. The inhibition effects of methanol extracts and sub-extracts (n-hexane, dichloromethane, ethyl acetate, n-butanol, and aqueous residue) of Leiotulus dasyanthus and Ferulago pauciradiata roots on carbonic anhydrase I and II isoenzymes were investigated in this research.