Effects of vitamin C and n-acetylcysteine against cyclophosphamide-induced genotoxicity in exfoliated bladder cells of mice in vivo

Gurbuz N., Ozkul A., Burgaz S.

JOURNAL OF BUON, cilt.14, sa.4, ss.647-652, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 4
  • Basım Tarihi: 2009
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.647-652
  • Anahtar Kelimeler: chemoprevention, exfoliated bladder cells, genotoxicity, micronucleus, N-acetylcysteine, vitamin C, ASCORBIC-ACID, MICRONUCLEI FREQUENCIES, INDUCED UROTOXICITY, EPITHELIAL-CELLS, BETA-CAROTENE, DNA-DAMAGE, CLASTOGENICITY, CHEMOPREVENTION, PREVENTION, CANCER
  • Gazi Üniversitesi Adresli: Evet

Özet

Purpose: To investigate the effects of vitamin C and N-acetylcysteine (NAC) against cyclophosphamide (CP)-induced genotoxic damage in exfoliated bladder cells of mice by micronucleus (MN) assay.