Effect of melatonin and n-acetylcysteine on hepatic injury in rat induced by methanol intoxication: a comparative study

Koksal, M.; Kurcer, Z.; Erdogan, D.; Iraz, M.; Tas, M.; Eren, M.; Aydogan, T.; Ulas, T.

Effect of melatonin and n-acetylcysteine on hepatic injury in rat induced by methanol intoxication: a comparative study

Koksal M., Kurcer Z., Erdogan D., Iraz M., Tas M., Eren M. A., ...More

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.16, no.4, pp.437-444, 2012 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 16 Issue: 4
Publication Date: 2012
Journal Name: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.437-444
Keywords: Methanol intoxication, Melatonin, N- acetyl cysteine, Hepatic injury Rat, Electron microscopy, LIPID-PEROXIDATION, ISCHEMIA-REPERFUSION, OXIDATIVE STRESS, FINE-STRUCTURE, LIVER-INJURY, VITAMIN-E, DAMAGE, ISCHEMIA/REPERFUSION, PHARMACOKINETICS, MORTALITY
Gazi University Affiliated: Yes

Abstract

Background: Methanol intoxication leads liver injury; in contrast melatonin and n-acetyl cysteine (NAC) are known to have protective effects on liver.