Effect of melatonin and n-acetylcysteine on hepatic injury in rat induced by methanol intoxication: a comparative study

Koksal M., Kurcer Z., Erdogan D., Iraz M., Tas M., Eren M. A., ...Daha Fazla

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, cilt.16, sa.4, ss.437-444, 2012 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 4
  • Basım Tarihi: 2012
  • Dergi Adı: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.437-444
  • Anahtar Kelimeler: Methanol intoxication, Melatonin, N- acetyl cysteine, Hepatic injury Rat, Electron microscopy, LIPID-PEROXIDATION, ISCHEMIA-REPERFUSION, OXIDATIVE STRESS, FINE-STRUCTURE, LIVER-INJURY, VITAMIN-E, DAMAGE, ISCHEMIA/REPERFUSION, PHARMACOKINETICS, MORTALITY
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Methanol intoxication leads liver injury; in contrast melatonin and n-acetyl cysteine (NAC) are known to have protective effects on liver.