Effect of melatonin and n-acetylcysteine on hepatic injury in rat induced by methanol intoxication: a comparative study


Koksal M., Kurcer Z., Erdogan D., Iraz M., Tas M., Eren M. A. , ...More

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.16, no.4, pp.437-444, 2012 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 4
  • Publication Date: 2012
  • Title of Journal : EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Page Numbers: pp.437-444
  • Keywords: Methanol intoxication, Melatonin, N- acetyl cysteine, Hepatic injury Rat, Electron microscopy, LIPID-PEROXIDATION, ISCHEMIA-REPERFUSION, OXIDATIVE STRESS, FINE-STRUCTURE, LIVER-INJURY, VITAMIN-E, DAMAGE, ISCHEMIA/REPERFUSION, PHARMACOKINETICS, MORTALITY

Abstract

Background: Methanol intoxication leads liver injury; in contrast melatonin and n-acetyl cysteine (NAC) are known to have protective effects on liver.