Involvement of galectin-3 in cadmium-induced cardiac toxicity

YAZIHAN N., Kocak M. K., Akcil E., Erdem O., Sayal A., Guven C., ...Daha Fazla

ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.11, sa.6, ss.479-484, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 6
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5152/akd.2011.130
  • Dergi Adı: ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.479-484
  • Anahtar Kelimeler: Cadmium, heart, galectin-3, caspase-3, tumor necrosis factor alpha, interleukin-6, HEART-FAILURE, MICE, MACROPHAGES, DYSFUNCTION, EXPRESSION, EXPOSURE, FIBROSIS
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: Accumulation of the wide spread environmental toxin cadmium (Cd) in tissues results in toxicity. Heart is one of the most effected tissues. Cd exposure induces inflammation in effected tissues. The present study was focused to evaluate roles of tumor necrosis factor alpha (TNF-alpha) and interleukin-6 (IL-6) in Cd toxicity and their relationships with galectin-3 levels.