CYTOTOXIC ACTIVITY STUDIES OF SOME PLATINUM(II) COMPLEXES WITH 2-SUBSTITUTEDBENZIMIDAZOLE LIGANDS
REVUE ROUMAINE DE CHIMIE, cilt.64, sa.9, ss.829-834, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 64 Sayı: 9
- Basım Tarihi: 2019
- Doi Numarası: 10.33224/rrch.2019.64.9.10
- Dergi Adı: REVUE ROUMAINE DE CHIMIE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.829-834
- Gazi Üniversitesi Adresli: Evet
Özet
In the present study, two Pt( II) complexes with 2-substitutedbenzimida-zole ligands were synthesized and evaluated for their in vitro cytotoxic activities on HeLa and MCF-7 cell lines. 3-[4,5-dimethylthiazole-2-yl]-2,5-diphenyltetrazolium bromide (MTT) test results showed that complex 2 which was found to be the more active than carboplatin was the most cytotoxic active compound against the HeLa and MCF-7 cell lines among the tested compounds.