Akademik Veri Yönetim Sistemi
INTERNATIONAL SCIENTIFIC COMPILATION RESEARCH CONGRESS-III, Ankara, Türkiye, 12 - 13 Şubat 2025, ss.699-709, (Tam Metin Bildiri)
Microbial biofilms play an important role in both medical device-associated and tissue-based infections. Globally, 80% of surgical site infections (CAE) contain microbial biofilm. Biofilms are microbial communities that are irreversibly attached to an interface, embedded in a matrix of extracellular polymeric substances of their own making. Biofilms are observed in a wide variety of medical biomaterials such as central venous catheters, urinary catheters, heart valves, orthopedic joint prostheses and internal fixation devices, surgical sutures (sutures), but the focus of clinical biofilm infections has been suture material. Surgical sutures (sutures) are considered a medical device for wound closure in healthcare applications. Surgical sutures may cause adverse effects on wound healing by creating inflammation in the wound area of the skin or organs after surgery. Despite advances in modern healthcare, surgical site infections (CAEs) can have high levels of infections that can inhibit wound healing after surgery. Medical device infections used during surgery constitute approximately 60% of hospital-acquired infections. In this context, it is necessary to develop antimicrobial surgical sutures with anti-infection and wound healing properties that can effectively inhibit bacterial growth and increase the healing rate.