Prognostic role of maspin expression in patients with cervical dysplasia and cervical cancer

Isci Bostanci E., GÜLER İ., UĞRAŞ DİKMEN A., ERDEM Ö., Guner H., ONAN M. A., ...Daha Fazla

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, cilt.46, sa.5, ss.759-764, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 5
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1111/jog.14225
  • Dergi Adı: JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.759-764
  • Anahtar Kelimeler: cervical cancer, cervical intraepithelial neoplasia, maspin, survival, SQUAMOUS-CELL CARCINOMA, POOR-PROGNOSIS, OVARIAN-CANCER, UP-REGULATION, ADENOCARCINOMA, LOCALIZATION, GENE, ANGIOGENESIS, GROWTH, LUNG
  • Gazi Üniversitesi Adresli: Evet

Özet

Aim Mammary serine protease inhibitor (maspin) acts as a tumor suppressor through the inhibition of cancer cell invasion and metastasis. Paradoxically, maspin levels are increased in some types of malignant cells. The aim of this study was to investigate the maspin expression in cervical dysplasia and cervical cancer, and to analyze its' relation with survival.