Prognostic role of maspin expression in patients with cervical dysplasia and cervical cancer

Isci Bostanci E., GÜLER İ., UĞRAŞ DİKMEN A., ERDEM Ö., Guner H., ONAN M. A., ...More

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, vol.46, no.5, pp.759-764, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 5
  • Publication Date: 2020
  • Doi Number: 10.1111/jog.14225
  • Journal Name: JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE
  • Page Numbers: pp.759-764
  • Keywords: cervical cancer, cervical intraepithelial neoplasia, maspin, survival, SQUAMOUS-CELL CARCINOMA, POOR-PROGNOSIS, OVARIAN-CANCER, UP-REGULATION, ADENOCARCINOMA, LOCALIZATION, GENE, ANGIOGENESIS, GROWTH, LUNG
  • Gazi University Affiliated: Yes

Abstract

Aim Mammary serine protease inhibitor (maspin) acts as a tumor suppressor through the inhibition of cancer cell invasion and metastasis. Paradoxically, maspin levels are increased in some types of malignant cells. The aim of this study was to investigate the maspin expression in cervical dysplasia and cervical cancer, and to analyze its' relation with survival.