A new steroidal alkaloid fromFritillaria michailovskyiFomin

Wang Y., Aamer M., Aslay M., Sener B., Khan F., Wahab A., ...Daha Fazla

NATURAL PRODUCT RESEARCH, cilt.36, sa.1, ss.361-366, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1080/14786419.2020.1786828
  • Dergi Adı: NATURAL PRODUCT RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, Aquatic Science & Fisheries Abstracts (ASFA), Biotechnology Research Abstracts, CAB Abstracts, CINAHL, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.361-366
  • Anahtar Kelimeler: Fritillaria michailovskyi, steroidal alkaloid, michainine, butyrylcholinesterase inhibitory activity
  • Gazi Üniversitesi Adresli: Evet

Özet

A new steroidal alkaloid, michainine (1), was isolated fromFritillaria michailovskyiFomin, along with nine known compounds2-10of different classes, including ribonucleoside, steroids, and fatty acids, which were isolated for the first time from this plant. Their structures were elucidated through extensive spectroscopic techniques, as well as by comparing the data in the literature. Furthermore, the dichloromethane fraction ofF. michailovskyishowed a positive butyrylcholinesterase inhibitory activity, along with non-cytotoxicity against 3T3 cell line.