A new steroidal alkaloid fromFritillaria michailovskyiFomin


Wang Y., Aamer M., Aslay M., Sener B., Khan F., Wahab A., ...More

NATURAL PRODUCT RESEARCH, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume:
  • Publication Date: 2020
  • Doi Number: 10.1080/14786419.2020.1786828
  • Title of Journal : NATURAL PRODUCT RESEARCH
  • Keywords: Fritillaria michailovskyi, steroidal alkaloid, michainine, butyrylcholinesterase inhibitory activity

Abstract

A new steroidal alkaloid, michainine (1), was isolated fromFritillaria michailovskyiFomin, along with nine known compounds2-10of different classes, including ribonucleoside, steroids, and fatty acids, which were isolated for the first time from this plant. Their structures were elucidated through extensive spectroscopic techniques, as well as by comparing the data in the literature. Furthermore, the dichloromethane fraction ofF. michailovskyishowed a positive butyrylcholinesterase inhibitory activity, along with non-cytotoxicity against 3T3 cell line.