A new steroidal alkaloid fromFritillaria michailovskyiFomin

Wang Y., Aamer M., Aslay M., Sener B., Khan F., Wahab A., ...More

NATURAL PRODUCT RESEARCH, vol.36, no.1, pp.361-366, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.1080/14786419.2020.1786828
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, Aquatic Science & Fisheries Abstracts (ASFA), Biotechnology Research Abstracts, CAB Abstracts, CINAHL, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.361-366
  • Keywords: Fritillaria michailovskyi, steroidal alkaloid, michainine, butyrylcholinesterase inhibitory activity
  • Gazi University Affiliated: Yes


A new steroidal alkaloid, michainine (1), was isolated fromFritillaria michailovskyiFomin, along with nine known compounds2-10of different classes, including ribonucleoside, steroids, and fatty acids, which were isolated for the first time from this plant. Their structures were elucidated through extensive spectroscopic techniques, as well as by comparing the data in the literature. Furthermore, the dichloromethane fraction ofF. michailovskyishowed a positive butyrylcholinesterase inhibitory activity, along with non-cytotoxicity against 3T3 cell line.