Microfluidic platforms based on SERS imaging and their point-of-care applications

TORUL H., Yıldırım E., TAMER U.

Current Opinion in Biomedical Engineering, vol.28, 2023 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Review
  • Volume: 28
  • Publication Date: 2023
  • Doi Number: 10.1016/j.cobme.2023.100510
  • Journal Name: Current Opinion in Biomedical Engineering
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: LFIA, Microfluidic platforms, Point-of-care, Raman spectroscopy, SERS
  • Gazi University Affiliated: Yes


Surface-enhanced Raman spectroscopy (SERS) imaging is one of the most prevalent and efficient molecular imaging techniques that may provide enhanced Raman signals of samples such as cells or biomolecules for highly accurate measurement. Furthermore, SERS imaging-based techniques can be adapted to portable systems, making them sufficient to be used for POC applications. In this review, we focused on prominent publications based on SERS imaging techniques in combination with microfluidics platforms for POC analysis of proteins, biomarkers and pathogens over the past five years.