The gender differences in the relaxation to levosimendan of human internal mammary artery

AKAR F., Manavbasi Y., Parlar A. I., Ulus A. T., Katircioglu S. F.

CARDIOVASCULAR DRUGS AND THERAPY, cilt.21, sa.5, ss.331-338, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 5
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1007/s10557-007-6047-x
  • Dergi Adı: CARDIOVASCULAR DRUGS AND THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.331-338
  • Anahtar Kelimeler: levosimendan, gender, human artery, potassium channels, relaxation, SPONTANEOUSLY HYPERTENSIVE-RATS, ISOLATED CORONARY-ARTERY, SMOOTH-MUSCLE, SEX-HORMONES, INTRAVENOUS LEVOSIMENDAN, POTASSIUM CHANNELS, CALCIUM SENSITIZER, HEART-FAILURE, BYPASS GRAFT, K+ CHANNEL
  • Gazi Üniversitesi Adresli: Evet

Özet

Purpose The mechanism of the vasorelaxation to levosimendan varies depending on the vascular bed and species studied. Here, we examined the vasorelaxation to levosimendan as well as its modification by various potassium channel antagonists in human internal mammary artery (IMA) obtained from male and female patients.