The Effect of Enalapril on Renal Resistive Index, Urine Electrolyte Levels and TGF-beta 1 Levels of Kidney Tissues in Rats with Unilateral Partial Ureteropelvic Junction Obstruction

Karakus, S.; Turkyilmaz, ZAFER; Sonmez, KAAN; Karabulut, RAMAZAN; Sivri, B.; Ogur, T.; Yilmaz, E.; Basaklar, A.

doi:10.1055/s-0031-1286340

The Effect of Enalapril on Renal Resistive Index, Urine Electrolyte Levels and TGF-beta 1 Levels of Kidney Tissues in Rats with Unilateral Partial Ureteropelvic Junction Obstruction

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Karakus S. C. , Turkyilmaz Z., Sonmez K., Karabulut R., Sivri B., Ogur T., ...More

EUROPEAN JOURNAL OF PEDIATRIC SURGERY, vol.21, no.6, pp.356-361, 2011 (SCI-Expanded)

Publication Type: Article / Article
Volume: 21 Issue: 6
Publication Date: 2011
Doi Number: 10.1055/s-0031-1286340
Journal Name: EUROPEAN JOURNAL OF PEDIATRIC SURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.356-361
Keywords: ureteropelvic junction obstruction, enalapril, arterial resistive index, urine electrolyte, transforming growth factor-beta 1, AQUAPORIN WATER CHANNELS, URETERAL OBSTRUCTION, ALTERED EXPRESSION, DOPPLER ULTRASOUND, RENIN-ANGIOTENSIN, NA TRANSPORTERS, HYDRONEPHROSIS, FIBROSIS
Gazi University Affiliated: Yes

Abstract

Background: This study aimed to investigate renal arterial resistive index measurements and urine electrolytes before and after enalapril therapy in a rat model of unilateral ureteropelvic obstruction. The transforming growth factor (TGF)-beta 1 response of the renal tissue was also investigated.