Akademik Veri Yönetim Sistemi
INFECTIOUS DISEASES AND CLINICAL MICROBIOLOGY, cilt.7, sa.4, ss.398-405, 2025 (ESCI, Scopus, TRDizin)
Objective: Real-time multiplex polymerase chain reaction (PCR) test increases the detection of viral respiratory tract infections. This study aimed to evaluate the effect of real-time multiplex PCR on antibiotic use in viral respiratory tract infections. Materials and Methods: This retrospective study included patients who underwent respiratory multiplex PCR tests. Patients were grouped into influenza-like illness, viral pneumonia, bacterial pneumonia, and co-infection. These groups were compared in terms of antibiotic use. Results: A total of 352 patients were included in the study. The most frequently detected viral agent was the human rhinovirus (24.3%). The frequency of antibiotic use and the median duration of antibiotic use were higher in the viral pneumonia group compared to the influenza-like illness group (p=0.003 and p<0.007). Conclusion: Despite a confirmed viral etiology by PCR, antibiotic use remained high, particularly in cases of viral pneumonia. These findings underscore the need for targeted antimicrobial stewardship interventions, including clinician education and integration of diagnostic-therapeutic approaches, to optimize antibiotic prescribing in respiratory infections.