Neurodevelopmental Outcomes of Pediatric Cardiac Extracorporeal Membrane Oxygenation Survivors With Central Cannulation.


Nakip O. S., KESİCİ S., Konuskan G. D., Yazici M., Konuskan B., BAYRAKCİ B.

American journal on intellectual and developmental disabilities, cilt.129, sa.5, ss.377-386, 2024 (SSCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 129 Sayı: 5
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1352/1944-7558-129.5.377
  • Dergi Adı: American journal on intellectual and developmental disabilities
  • Derginin Tarandığı İndeksler: Social Sciences Citation Index (SSCI), Scopus, PASCAL, Periodicals Index Online, Applied Science & Technology Source, Child Development & Adolescent Studies, CINAHL, EBSCO Education Source, Education Abstracts, Educational research abstracts (ERA), EMBASE, ERIC (Education Resources Information Center), MEDLINE, MLA - Modern Language Association Database, Psycinfo
  • Sayfa Sayıları: ss.377-386
  • Anahtar Kelimeler: cognitive dysfunction, critical care, developmental, ECMO, neuromonitoring
  • Gazi Üniversitesi Adresli: Hayır

Özet

Extracorporeal life support, such as pediatric cardiac extracorporeal membrane oxygenation (ECMO), is associated with significant mortality and morbidity risk. This study evaluated cardiac ECMO survivors with central cannulation and found that 51.1% were discharged from the hospital. The study also revealed high rates of developmental delay (82.7%), motor dysfunction (58.8%), and cognitive dysfunction (70.6%) among survivors. No significant correlation was found between the duration of ECMO, age at ECMO, pre-ECMO maximum lactate levels, and cognitive scores. Participants with motor dysfunction were significantly younger (p = 0.04). PRISM scores of those with an abnormal developmental status were significantly higher (p = 0.03). Logistic regression analysis did not show a significantly increased risk. Factors such as age, disease severity, and ECMO itself were identified as potential contributors to neurodevelopmental delay.