Effect of the Topical Use of the Antioxidant Taurine on the Two Basement Membrane Proteins of Regenerating Oral Gingival Epithelium


GÜLTEKİN S. E., Senguven B., Sofuoglu A., Taner L., Koch M.

JOURNAL OF PERIODONTOLOGY, vol.83, no.1, pp.127-134, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 83 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.1902/jop.2011.100568
  • Journal Name: JOURNAL OF PERIODONTOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.127-134
  • Keywords: Antioxidants, collagen, extracellular matrix, gingival hyperplasia, pathology, oral, wound healing, MARMOSET CALLITHRIX-JACCHUS, COLLAGEN TYPE-IV, IMMUNOHISTOCHEMICAL DISTRIBUTION, JUNCTIONAL EPITHELIUM, LAMININ, HEALTHY, SKIN, RAT, KERATINIZATION, LOCALIZATION
  • Gazi University Affiliated: Yes

Abstract

Background: The essential amino acid taurine has important physiologic and pathologic roles, and has been shown to have osmoregulatory, antioxidative, antiapoptotic, anti-inflammatory, and antilipid activities. However, the response of oral gingival epithelium to taurine during wound healing remains unclear. The goal of this study is to evaluate the expression of laminin 5 and Type IV collagen histologically in regenerating gingival epithelium after direct application of taurine on incised human gingival samples.