Effect of picroside II on erythrocyte deformability and lipid peroxidation in rats subjected to hind limb ischemia reperfusion injury


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Comu F. M., Kilic Y., ÖZER A., Kirisci M., DURSUN A. D., TATAR T., ...Daha Fazla

DRUG DESIGN DEVELOPMENT AND THERAPY, cilt.10, ss.927-931, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10
  • Basım Tarihi: 2016
  • Doi Numarası: 10.2147/dddt.s95418
  • Dergi Adı: DRUG DESIGN DEVELOPMENT AND THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.927-931
  • Anahtar Kelimeler: hind limb ischemia reperfusion injury, lipid peroxidation, malondialdehyde, nitric oxide, erythrocyte deformability, picroside II, MYOCARDIAL-ISCHEMIA, SKELETAL-MUSCLE, NITRIC-OXIDE, SUPEROXIDE, MODEL
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Ischemia reperfusion injury (I/R) in hind limb is a frequent and important clinical phenomenon. Many structural and functional damages are observed in cells and tissues in these kinds of injuries. In this study, we aimed to evaluate the effect of picroside II on lipid peroxidation and erythrocyte deformability during I/R in rats.