Ischemic modified albumin as a new biomarker in predicting oxidative stress in alopecia areata

Atas H., Gonul M., Ozturk Y., KAVUTÇU M.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.49, sa.1, ss.129-138, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.3906/sag-1708-35
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.129-138
  • Anahtar Kelimeler: Biomarkers, alopecia areata, oxidative stress, antioxidative system, ischemia-modified albumin, LIPID-PEROXIDATION, SUPEROXIDE-DISMUTASE, ANTIOXIDANT ENZYMES, CATALASE LEVELS, VITILIGO, MARKERS, LEVEL
  • Gazi Üniversitesi Adresli: Evet

Özet

Background/aim: Results show that oxidative stress is a pathophysiologic factor for alopecia areata (AA); however, the markers used can be confounding. Thus, we aimed to investigate the role of oxidative stress in the pathogenesis of AA through an evaluation of ischemia-modified albumin (IMA); other markers of the oxidant/antioxidant system, such as SOD, CAT, GSH-ST, and MDA; and contributing clinical risk factors.