Ischemic modified albumin as a new biomarker in predicting oxidative stress in alopecia areata


Atas H., Gonul M., Ozturk Y., KAVUTÇU M.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.49, no.1, pp.129-138, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.3906/sag-1708-35
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.129-138
  • Keywords: Biomarkers, alopecia areata, oxidative stress, antioxidative system, ischemia-modified albumin, LIPID-PEROXIDATION, SUPEROXIDE-DISMUTASE, ANTIOXIDANT ENZYMES, CATALASE LEVELS, VITILIGO, MARKERS, LEVEL
  • Gazi University Affiliated: Yes

Abstract

Background/aim: Results show that oxidative stress is a pathophysiologic factor for alopecia areata (AA); however, the markers used can be confounding. Thus, we aimed to investigate the role of oxidative stress in the pathogenesis of AA through an evaluation of ischemia-modified albumin (IMA); other markers of the oxidant/antioxidant system, such as SOD, CAT, GSH-ST, and MDA; and contributing clinical risk factors.