PSMA-Avid Liver Metastasis in a Case of Prostate Carcinoma and Poorly Differentiated Thyroid Carcinoma

Coskun M., Aydos U., Akdemir Ü. Ö., Yalcin M. M., Toruner F. S.

CLINICAL NUCLEAR MEDICINE, cilt.49, sa.8, 2024 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Editöre Mektup
  • Cilt numarası: 49 Sayı: 8
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1097/rlu.0000000000005299
  • Dergi Adı: CLINICAL NUCLEAR MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Anahtar Kelimeler: 68Ga-PSMA PET, liver metastasis, poorly differentiated thyroid carcinoma, prostate carcinoma
  • Gazi Üniversitesi Adresli: Evet

Özet

Although PSMA-targeted PET imaging is predominantly used for prostate carcinoma (PC), it has also been reported for thyroid carcinoma (TC). A 77-year-old man had a liver metastasectomy for poorly differentiated TC, which had elevated F-18-FDG uptake. Two years later, he was diagnosed with acinar-type modified Gleason score of 7 (3 + 4) PC. Four years later, he had metastatic liver lesions that had no radioactive iodine and F-18-FDG avidity. These lesions were Ga-68-PSMA avid, and the biopsy confirmed TC metastasis. This case emphasizes the importance of Ga-68-PSMA-based imaging in poorly differentiated TC and pathological confirmation for lesions that were Ga-68-PSMA-positive.