The Neuroprotective Effects of Rituximab in Rat Spinal Cord Injury Model: An Immunohistochemical Study

Menekse G., Daglioglu E., Nacar O. A., Polat E., Ozdol C., Dalgic A., ...Daha Fazla

TURKISH NEUROSURGERY, cilt.23, sa.6, ss.783-790, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 6
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5137/1019-5149.jtn.8051-13.0
  • Dergi Adı: TURKISH NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.783-790
  • Anahtar Kelimeler: B-lymphocyte, CD20, IL1 beta, Rats, Rituximab, Spinal cord injury, TNF-alpha, IMMUNE-SYSTEM, CNS, THERAPY, CELLS
  • Gazi Üniversitesi Adresli: Evet

Özet

AIM: In the present study, we investigate the neuroprotective effects of rituximab, a monoclonal antibody directed towards B cell mediated humoral immunity, on a rat spinal cord injury (SCI) model with immunohistochemical methods.