Quetiapine use for the treatment of manic episode during pregnancy

Cabuk D., Sayin A., Derinoez O. , Biri A.

ARCHIVES OF WOMENS MENTAL HEALTH, cilt.10, sa.5, ss.235-236, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Konu: 5
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1007/s00737-007-0196-6
  • Sayfa Sayıları: ss.235-236


The foregoing is a case report about a 30-year-old woman, who was referred to our psychiatry clinic with a clinical picture of manic episode, at the 21st week of her first pregnancy. She had a history of bipolar affective disorder for 12 years, had two previous manic episodes and had stopped taking lithium 6 months ago because of her plans to become pregnant. Quetiapine was begun and the dose was slowly increased to 1200 mg/day after 2 weeks. She continued to receive quetiapine throughout her pregnancy. Her obstetrical and perinatal examinations were done by a consultant obstetrician. At the follow-up, she had given birth to a boy, at 39th week of her pregnancy, with an Apgar score of 10. Follow-up of the infant up to 3 months reveals normal physical and psychomotor development. The pros and cons of quetiapine use during pregnancy are discussed.