Copy For Citation
Kaya A. O., Gunel N., Benekli M., Akyurek N., Buyukberber S., Tatli H., ...More
JOURNAL OF BUON, vol.17, no.4, pp.663-668, 2012 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
17
Issue:
4
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Publication Date:
2012
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Journal Name:
JOURNAL OF BUON
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.663-668
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Keywords:
breast cancer, tumor hypoxia, HIF-1 alpha, CA IX, prognosis, PROGNOSTIC MARKER, FOLLOW-UP, CA-IX, FACTOR-1-ALPHA, EXPRESSION, RADIOTHERAPY, CELLS
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Gazi University Affiliated:
Yes
Abstract
Purpose: Hypoxia is common in many solid tumors such as breast, head-neck, and soft tissue malignancies. Hypoxia causes overexpression of hypoxia inducible factor-1 alpha (HIF-1 alpha) and carbonic anhydrase IX (CA IX) which are associated with unfavorable prognosis in breast cancer. In our study, we evaluated HIF-1 alpha and CA IX expression in patients with breast cancer.