JOURNAL OF BUON, vol.17, no.4, pp.663-668, 2012 (SCI-Expanded)
Article / Article
JOURNAL OF BUON
Science Citation Index Expanded (SCI-EXPANDED), Scopus
breast cancer, tumor hypoxia, HIF-1 alpha, CA IX, prognosis, PROGNOSTIC MARKER, FOLLOW-UP, CA-IX, FACTOR-1-ALPHA, EXPRESSION, RADIOTHERAPY, CELLS
Gazi University Affiliated:
Purpose: Hypoxia is common in many solid tumors such as breast, head-neck, and soft tissue malignancies. Hypoxia causes overexpression of hypoxia inducible factor-1 alpha (HIF-1 alpha) and carbonic anhydrase IX (CA IX) which are associated with unfavorable prognosis in breast cancer. In our study, we evaluated HIF-1 alpha and CA IX expression in patients with breast cancer.