Efficacy and safety of Saccharomyces boulardii in the 14-day triple anti-Helicobacter pylori therapy: A prospective randomized placebo-controlled double-blind study


Cindoruk M., Erkan G., Karakan T., Dursun A., Unal S.

HELICOBACTER, vol.12, no.4, pp.309-316, 2007 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 12 Issue: 4
  • Publication Date: 2007
  • Doi Number: 10.1111/j.1523-5378.2007.00516.x
  • Journal Name: HELICOBACTER
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.309-316
  • Keywords: H. pylori, S. boulardii, eradication, triple therapy, ANTIBIOTIC-ASSOCIATED DIARRHEA, GNOTOBIOTIC MURINE MODEL, ERADICATION THERAPY, CONTROLLED TRIAL, IN-VITRO, INFECTION, PREVENTION, PROBIOTICS, GASTRITIS, CHILDREN
  • Gazi University Affiliated: Yes

Abstract

Background: Recent studies indicate a potential role of Saccharomyces boulardii in the prevention of Helicobacter pylori treatment-related side-effects and also in improvement of eradication rate. Our aim is to investigate the efficacy and safety of S. boulardii in the prevention of side-effects related to H. pylori eradication. The secondary aim of the study was to define the effect of S. boulardii oil the eradication success of anti-H. pylori therapy.