Unusual Presentation of an Adenocarcinoma of the Lung Metastasizing to the Mandible, Including Molecular Analysis and a Review of the Literature

GÜLTEKİN, SİBEL; Senguven, BURCU; IŞIK GÖNÜL, İPEK; Okur, Begum; Buettner, Reinhard

doi:10.1016/j.joms.2016.06.004

Unusual Presentation of an Adenocarcinoma of the Lung Metastasizing to the Mandible, Including Molecular Analysis and a Review of the Literature

Atıf İçin Kopyala

GÜLTEKİN S. E., Senguven B., IŞIK GÖNÜL İ., Okur B., Buettner R.

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, cilt.74, sa.10, 2016 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 74 Sayı: 10
Basım Tarihi: 2016
Doi Numarası: 10.1016/j.joms.2016.06.004
Dergi Adı: JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Gazi Üniversitesi Adresli: Evet

Özet

Lung cancer is the most frequent cause of cancer-related death worldwide. Metastases of non-small cell lung carcinoma to the oral and maxillofacial region are rare. Thus, the diagnosis of a metastatic lesion in the oral cavity is challenging to the clinician and to the pathologist. This report presents a case of a 72-year-old man with metastatic lung adenocarcinoma located in the posterior mandibular region. Next-generation sequencing analysis showed no important mutations in the relevant genes except in the TP53 tumor suppressor gene. (C) 2016 American Association of Oral and Maxillofacial Surgeons