PEDIATRIC BLOOD & CANCER, vol.53, no.1, pp.95-97, 2009 (SCI-Expanded)
Article / Article
PEDIATRIC BLOOD & CANCER
Science Citation Index Expanded (SCI-EXPANDED), Scopus
dyskeratosis congenita, limbal insufficiency, stem cell, telomere length, MARROW FAILURE SYNDROMES, STEM-CELLS, TELOMERE MAINTENANCE, BLOOM-SYNDROME, DISORDER
Gazi University Affiliated:
We describe a newly diagnosed Turkish adolescent female with Dyskeratosis congenita along with the novel ocular finding of corneal limbal insufficiency. Corneal limbal insufficiency was suggested to be a premature aging sign resulting from a deficiency in corneal stein cell activity, a biological process caused by underlying telomeric defect in this disease. Pediatr Blood Cancer 2009;53:95-97. (C) 2()09 Wiley-Liss, Inc.