Histiocytic sarcoma: PET-CT evaluation of a rare entity

Yaman E., Ozturk B., ERDEM O. A. , Gokcora N., Coskun U., Uluoglu O., ...Daha Fazla

ANNALS OF NUCLEAR MEDICINE, cilt.22, sa.8, ss.715-717, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Konu: 8
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1007/s12149-008-0175-7
  • Sayfa Sayıları: ss.715-717


Histiocytic sarcoma is a rare malignancy of hematopoietic origin. Lymph nodes, skin, and extranodal sites, especially gastrointestinal tract, are commonly involved. Some cases reported in the past as non-Hodgkin's lymphoma are now classifi ed as histiocytic sarcoma by detailed immunohistochemical studies. Patients with clinically localized disease have a good prognosis whereas those with lymphatic involvement have an aggressive course. In our case, histiocytic sarcoma was detected, originating from the skin over the left shoulder associated with disseminated lymphadenopathy. A positron emission tomography/computed tomography examination was done for evaluating the extent of the disease which showed pathologic increased 18F-fl uorodeoxyglucose uptake in the lymph nodes, indicating widespread disease. The pertinent literature is reviewed.