N-acetylcysteine may prevent severe intestinal damage in necrotizing enterocolitis


Tayman C., Tonbul A., Kosus A., HIRFANOĞLU İ. M. , Uysal S., Haltas H., ...More

JOURNAL OF PEDIATRIC SURGERY, vol.47, no.3, pp.540-550, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.1016/j.jpedsurg.2011.09.051
  • Title of Journal : JOURNAL OF PEDIATRIC SURGERY
  • Page Numbers: pp.540-550
  • Keywords: Necrotizing enterocolitis, N-acetylcysteine, Protection, Newborn, Rat, NEONATAL-RAT MODEL, ACETYL-L-CYSTEINE, BACTERIAL TRANSLOCATION, OXIDATIVE DAMAGE, INJURY, NEWBORN, OXYGEN, COLONIZATION, PATHOGENESIS, MANAGEMENT

Abstract

Objective: The aim of this study was to evaluate the preventive effect of N-acetylcysteine (NAC) on the development of necrotizing enterocolitis (NEC) in an experimental rat model.