In this study, the effects of machining parameters on the vibrations which occur in machine tool, cutting forces, workpiece surface roughness are investigated in the milling operations. In the experiments, 132, 200, 308 m/min cutting speed, 0.05, 0.1, 0.15, 0.2 mm/tooth feed rate, 1, 1.5 mm cutting depth and 1,2,4 cutting edge number are used as machining parameters. With these machining parameters, chip has removed on the AISI 1050 steel material which is dimension 100x50x20 mm. 72 test were carried out in this study. Values of vibrations, cutting forces and surface roughness have been measured during the machining operations. After, to determine the effects to results of machining parameters and in order to compose a mathematical model analysis of variance (ANOVA) and quadratic multiple regression have been performed. According to the experiment results, it has been seen that with the increasing of cutting edge number, cutting depth and feed rate, then all other results have also increased. While, increasing of cutting speed is affecting vibration acceleration level negatively, it gives a positive effect to cutting force and surface quality. Increasing of vibration acceleration levels has caused the rising of surface roughness. As a result, it has been defined that vibration has a negative effect on the surface roughness.