Does preemptive gabapentin modulate cytokine response in total knee arthroplasty? A placebo controlled study

Erkilic, Ezgi; Kesimci, Elvin; Sahin, Duygu; Bektaser, Bulent; Yalcin, Nadir; Ellik, Suleyman; Sepici Dinçel, AYLİN

doi:10.17219/acem/68630

Does preemptive gabapentin modulate cytokine response in total knee arthroplasty? A placebo controlled study

Erkilic E., Kesimci E., Sahin D., Bektaser B., Yalcin N., Ellik S., ...Daha Fazla

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, cilt.27, sa.4, ss.487-491, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 27 Sayı: 4
Basım Tarihi: 2018
Doi Numarası: 10.17219/acem/68630
Dergi Adı: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.487-491
Anahtar Kelimeler: preemptive, gabapentin, postoperative analgesia, serum IL-6, serum TNF, POSTOPERATIVE PAIN-CONTROL, NECROSIS-FACTOR-ALPHA, FUNCTIONAL RECOVERY, DOUBLE-BLIND, NEUROPATHIC PAIN, RAT MODEL, SURGERY, TRIAL, REPLACEMENT, PARECOXIB
Gazi Üniversitesi Adresli: Evet

Özet

Background. Gabapentin, as a structural analogue of gamma-aminobutyric acid, has been investigated to provide Funding sources pain relief in the early postoperative period following various surgical interventions.