Does preemptive gabapentin modulate cytokine response in total knee arthroplasty? A placebo controlled study


Erkilic E., Kesimci E., Sahin D., Bektaser B., Yalcin N., Ellik S., ...More

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, vol.27, no.4, pp.487-491, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.17219/acem/68630
  • Title of Journal : ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
  • Page Numbers: pp.487-491
  • Keywords: preemptive, gabapentin, postoperative analgesia, serum IL-6, serum TNF, POSTOPERATIVE PAIN-CONTROL, NECROSIS-FACTOR-ALPHA, FUNCTIONAL RECOVERY, DOUBLE-BLIND, NEUROPATHIC PAIN, RAT MODEL, SURGERY, TRIAL, REPLACEMENT, PARECOXIB

Abstract

Background. Gabapentin, as a structural analogue of gamma-aminobutyric acid, has been investigated to provide Funding sources pain relief in the early postoperative period following various surgical interventions.