Microemboli May Link Spreading Depression, Migraine Aura, and Patent Foramen Ovale

Nozari A., Dilekoz E., Sukhotinsky I., Stein T., Eikermann-Haerter K., Liu C., ...More

ANNALS OF NEUROLOGY, vol.67, no.2, pp.221-229, 2010 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 67 Issue: 2
  • Publication Date: 2010
  • Doi Number: 10.1002/ana.21871
  • Journal Name: ANNALS OF NEUROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.221-229
  • Gazi University Affiliated: Yes

Abstract

Objective: Patent foramen ovale and pulmonary arteriovenous shunts are associated with serious complications such as cerebral emboli, stroke, and migraine with aura. The pathophysiological mechanisms that link these conditions are unknown. We aimed to establish a mechanism linking microembolization to migraine aura in an experimental animal model.