Research Information System
Turkish Archives of Pediatrics, vol.60, no.5, pp.524-530, 2025 (ESCI, Scopus, TRDizin)
Objective: Although a limited number of studies have assessed the impact of the Coronavirus disease 2019 (COVID-19) pandemic on adults with eosinophilic esophagitis (EoE), there are no data on children. This study aimed to assess the impact of the COVID-19 pandemic on children with EoE, including long-term follow-up, treatment adherence, COVID-19 infection, and vaccination status. Materials and Methods: Treatment adherence, symptoms, and endoscopic-pathological findings were compared at the beginning and the end of the first and second years of the pan-demic. The COVID-19 infection and vaccination status were also assessed. Results: The study included 66 children (median age 13.2 years) with EoE. Both treatment adherence and endoscopic follow-up decreased significantly during the pandemic compared to the beginning (P < .001 and P < .001, respectively). No strictures were observed. Twenty-two patients underwent endoscopy both before and during the pandemic, showing increased total eosinophilic esophagitis endoscopic reference score (EREFS) and peak eosinophil counts (P = .045 and P = .08, respectively). Among children aged 12 and older, 66% were vaccinated against COVID-19. Infection with COVID-19 was detected in 24 children (36.3%), with asymp-tomatic or mild symptoms in 95.8% of cases. Conclusion: No strictures developed during the first 2 years of the pandemic in children with EoE. However, increased tissue eosinophilia and EREFS scores suggest a possible risk of fibro-stenosis if treatment adherence remains low. Eosinophilic esophagitis does not seem to pose an increased risk for COVID-19 infection in children.