Retrospective evaluation of routine biochemical blood parameters in children with cerebral palsi


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Gök Dağıdır H., Bukan N., Arhan E., Tombul N., Ülgen Temel E.

3rd International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2020), Ankara, Turkey, 19 - 20 March 2020, pp.29-33

  • Publication Type: Conference Paper / Full Text
  • City: Ankara
  • Country: Turkey
  • Page Numbers: pp.29-33
  • Gazi University Affiliated: Yes

Abstract

Cerebral palsy (Cp) is a persistent developmental disorder that is common in childhood and affects movement and posture throughout life.

Along with motor dysfunction, which is the main finding of the disease; Sensory cognitive problems, epilepsy, communication perception problems, oral motor failure and related nutritional problems, behavioral disorders, orthopedic disorders, neurological dysfunctions, convulsions, chronic lung problems and sleep problems are common.

The prevalence of Cp is approximately 2-3.5 per 1000 live births. In addition, this rate increases to 65 in 1000 live births in premature births below 1500 g.

The aim of this retrospective study was to evaluate the biochemical blood parameters of children with Cp.

The study included 50 children with Cp aged between 0 and 18 years and 50 healthy children as a control group. The Cp group was selected from the children with Cp diagnosis in the Department of Pediatric Neurology at Gazi University Faculty of Medicine between 2018-2019 and the control group was selected from the Children's Health Unit. Control group; was selected from patients who were in the same age range as the Cp group and who did not have any neurological disease. For the study, the ethics committee permission was obtained from the meeting on 28.05.2018 (decision number: 430) from Gazi University Clinical Research Ethics Committee. In two groups, routine biochemical parameters were evaluated retrospectively. According to our study; creatinine, calcium, phosphorus, sodium, folic acid, albumin ratios were significantly different between Cp and control group (p<0,05).

As a result; in children with cerebral palsy there may be bone metabolism disorders. This quality of life in chronic monitoring of children so that these disorders can be corrected early it is important to be noticed and treated.