Renal safety and extrahepatic defluorination of sevoflurane in hepatic transplantations

Kanbak, M.; Karagoz, A.; Erdem, N.; Oc, B.; Saricaoglu, F.; Ertas, NUSRET; Berkkan, AYSEL; Abbasoglu, O.; Aypar, U.

doi:10.1016/j.transproceed.2007.01.081

Renal safety and extrahepatic defluorination of sevoflurane in hepatic transplantations

Atıf İçin Kopyala

Kanbak M., Karagoz A. H., Erdem N., Oc B., Saricaoglu F., Ertas N., ...Daha Fazla

TRANSPLANTATION PROCEEDINGS, cilt.39, sa.5, ss.1544-1548, 2007 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 39 Sayı: 5
Basım Tarihi: 2007
Doi Numarası: 10.1016/j.transproceed.2007.01.081
Dergi Adı: TRANSPLANTATION PROCEEDINGS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1544-1548
Gazi Üniversitesi Adresli: Evet

Özet

Background. The main metabolic pathway for defluorination of sevoflurane in the liver produces inorganic fluoride (171). The metabolism and effect of sevoflurane on the kidney is not clear during anhepatic phase in liver transplantation. The goal of the present study was to investigate the metabolism and renal effect of sevoflurane by measuring plasma and urine inorganic fluoride, urinary N-acetyl-glucosaminidase (NAG), and plasma creatinine levels in patients undergoing liver transplantations.