Pro-oxidative/antioxidative imbalance: a key indicator of adverse outcome in hematopoietic stem cell transplantation

Yegin Z. A., Pasaoglu H., Aki S. Z., Ozkurt Z. N., Demirtas C., Yagci M., ...Daha Fazla

INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, cilt.33, sa.4, ss.414-423, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1111/j.1751-553x.2011.01297.x
  • Dergi Adı: INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.414-423
  • Anahtar Kelimeler: Iron overload, oxidative stress, ferritin, nontransferrin bound iron, stem cell transplantation, BONE-MARROW-TRANSPLANTATION, TRANSFERRIN-BOUND IRON, PRETRANSPLANTATION SERUM FERRITIN, SINUSOIDAL OBSTRUCTION SYNDROME, LIVER DYSFUNCTION, PROGNOSTIC IMPACT, OXIDATIVE STRESS, RISK-FACTOR, OVERLOAD, RECIPIENTS
  • Gazi Üniversitesi Adresli: Evet

Özet

Introduction: Pretransplantation iron overload (IO) is considered as a predictor of adverse outcome in hematopoietic stem cell transplantation (HSCT). Peroxidative tissue injury caused by IO leads to progressive organ dysfunction.