Nanoporous Polymeric Nanofibers Based on Selectively Etched PS-b-PDMS Block Copolymers


Demirel G. B. , BÜYÜKSERİN F., Morris M. A. , DEMİREL G.

ACS APPLIED MATERIALS & INTERFACES, vol.4, no.1, pp.280-285, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 4 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.1021/am201331b
  • Title of Journal : ACS APPLIED MATERIALS & INTERFACES
  • Page Numbers: pp.280-285

Abstract

One-dimensional nanoporous polymeric nanofibers have been fabricated within an anodic aluminum oxide (AAO) membrane by a facile approach based on selective etching of poly(dimethylsiloxane) (PDMS) domains in polystyrene-block-poly(dimethylsiloxane) (PS-b-PDMS) block copolymers that had been formed within the AAO template. It was observed that prior to etching, the well-ordered PS-b-PDMS nanofibers are solid and do not have any porosity. The postetched PS nanofibers, on the other hand, had a highly porous structure having about 20-50 nm pore size. The nanoporous polymeric fibers were also employed as a drug carrier for the native, continuous, and pulsatile drug release using Rhodamine B (RB) as a model drug. These studies showed that enhanced drug release and tunable drug dosage can be achieved by using ultrasound irradiation.