Purpose: The purpose of this study was to compare the clinical and radiographic success of Biodentine (TM) and mineral trioxide aggregate (MTA) pulpotomy in primary molars. Methods: Thirty-two four-to nine-year-olds were included in this study. The primary molars were randomly assigned to the Biodentine (TM) and MTA groups. After corona' pulp removal and hemostasis, the remaining pulp tissue was covered with Biodentine or MTA. All teeth were restored with stainless steel crowns. Clinical and radiographic successes and failures were recorded at six-, 12-, 18-and 24-month follow-ups. Data were statistically analyzed using Mann-Whitney U and Wilcoxon tests. Results: The 24-month follow-up evaluations revealed that the clinical success rates were 96.8 percent (30 out of 31) for both Biodentine (TM) and MTA. The radiographic success rates at 24 months were 93.6 percent (29 out of 31) for Biodentine (TM) and 871 percent (27 out of 31) for MTA. No significant differences were found among the groups at all follow-up appointments (P>0.05) Conclusion: Biodentine (TM) and mineral trioxide aggregate did, not differ significantly in combined clinical and radiographic success after 24 months.