CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR GENE MUTATIONS IN PATIENTS WITH MASSIVE NASAL POLYPOSIS


KIZIL Y., ERGÜN M. A. , AYDİL U., Uslu S.

NOBEL MEDICUS, vol.9, no.1, pp.17-20, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 1
  • Publication Date: 2013
  • Journal Name: NOBEL MEDICUS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.17-20
  • Gazi University Affiliated: Yes

Abstract

Objective: Isolated features of cystic fibrosis can be seen without classical cystic fibrosis clinical symptomps. In some instances, cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations can result in male infertility, pancreas involvement or lung problems with negative sweat test. Nasal polyposis is also one of the prominent components of cystic fibrosis clinic and theoretically may occur alone with CFTR gene mutations. In this study, we aim to detect the frequency of common cystic fibrosis transmembrane conductance regulator gene mutations in massive nasal polyposis patients.