CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR GENE MUTATIONS IN PATIENTS WITH MASSIVE NASAL POLYPOSIS


KIZIL Y. , ERGÜN M. A. , AYDİL U. , Uslu S.

NOBEL MEDICUS, vol.9, no.1, pp.17-20, 2013 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 1
  • Publication Date: 2013
  • Title of Journal : NOBEL MEDICUS
  • Page Numbers: pp.17-20

Abstract

Objective: Isolated features of cystic fibrosis can be seen without classical cystic fibrosis clinical symptomps. In some instances, cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations can result in male infertility, pancreas involvement or lung problems with negative sweat test. Nasal polyposis is also one of the prominent components of cystic fibrosis clinic and theoretically may occur alone with CFTR gene mutations. In this study, we aim to detect the frequency of common cystic fibrosis transmembrane conductance regulator gene mutations in massive nasal polyposis patients.