CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR GENE MUTATIONS IN PATIENTS WITH MASSIVE NASAL POLYPOSIS

KIZIL Y., ERGÜN M. A., AYDİL U., Uslu S.

NOBEL MEDICUS, cilt.9, sa.1, ss.17-20, 2013 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 1
  • Basım Tarihi: 2013
  • Dergi Adı: NOBEL MEDICUS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.17-20
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: Isolated features of cystic fibrosis can be seen without classical cystic fibrosis clinical symptomps. In some instances, cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations can result in male infertility, pancreas involvement or lung problems with negative sweat test. Nasal polyposis is also one of the prominent components of cystic fibrosis clinic and theoretically may occur alone with CFTR gene mutations. In this study, we aim to detect the frequency of common cystic fibrosis transmembrane conductance regulator gene mutations in massive nasal polyposis patients.