Akademik Veri Yönetim Sistemi
TURKISH JOURNAL OF MARITIME AND MARINE SCIENCES, cilt.10, sa.4, ss.2006-2016, 2024 (Hakemli Dergi)
The objective of the present study was to investigate the antimicrobial properties of a chitosan-based cream. To achieve this, the antimicrobial effects of a cream enriched with chitosan were compared with those of a control group. Chitosan, sourced from crayfish obtained frozen from Eğirdir Lake, Eğirdir, Isparta, served as the primary material. The study involved a comparison between control (F1) and treatment (F2) groups. While both cream formulations exhibited bacterial inhibition, only the F1 formulation demonstrated a significant reduction in viable microorganisms for C. albicans. The cytotoxicity assessment revealed a concentration-dependent increase in the cytotoxic effects of the samples. Notably, the F1 formulation exhibited higher toxicity to healthy cells compared to the F2 formulation. In conclusion, further investigation is necessary to understand the mechanisms underlying their cytotoxic effects and to optimize their formulations to enhance biocompatibility. Moreover, the chitosan-based cream developed in this study demonstrated notable antimicrobial efficacy against the tested bacteria.