Akademik Veri Yönetim Sistemi
Journal of the Indian Chemical Society, cilt.103, sa.7, 2026 (SCI-Expanded, Scopus)
The novel Ni(II) {[Ni(dpc)(abt)(H2O)2], 1 } and Cu(II) {[Cu(dpc)(abt)2], 2 , abt = 2-amino-5,6-dimethylbenzothiazole, H2dpc = dipicolinic acid) complexes were synthesized. The structures of 1 and 2 were characterized by elemental analysis, AAS, single crystal X-ray diffraction, FT-IR, UV, magnetic measurement, and molar conductivity. The structure of 1 contains one Ni(II) ion, one dpc2− ion, one abt molecule, and two coordinated water molecules. The structure of 2 contains one Cu(II) ion, one dpc2− ion and two abt molecules. In the structure of complexes, one tridentate dpc ligand and one for 1 and two for 2 abt molecules were bound to the metal ion. Based on these analysis methods, all complexes were observed to have a non-ionic octahedral for 1 and a distorted square pyramidal for 2 structures. Furthermore, the antimicrobial properties of abt, H2dpc, 1 and 2 have also been tested against C. parapsilosis, C. krusei, C. albicans (antifungal activity), and E. Coli, P. aeruginosa, B. subtilis, S. aureus, L. monocytogenes, E. faecalis (antibacterial activity). The results were compared with those obtained using the control compounds Fluconazole and Ketoconazole (antifungal activity) and Vancomycin, Levofloxacin, Cefepime, and Chloramphenicol (antibacterial activity). As a result of activity studies, newly synthesized compounds show activity against bacteria and yeasts. The best antifungal activity results were observed for all compounds (except H2dpc) against C. albicans , 1 and 2 against C. parapsilosis , and 1 against C. krusei . In contrast, the best antibacterial results were observed for all compounds against S. aureus , 1 and 2 against E. faecalis , abt against B. subtilis , all compounds (except H2dpc) against E. coli , 1 and 2 against L. monocytogenes , and 1 and 2 against P. aeruginosa . All compounds are posited to have potential applications for inhibiting bacterial and yeast growth.