Nitric oxide level of aqueous humour after photorefractive keratectomy in Guinea pigs
Gazi Medical Journal, cilt.12, sa.2, ss.55-58, 2001 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 12 Sayı: 2
- Basım Tarihi: 2001
- Dergi Adı: Gazi Medical Journal
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.55-58
- Gazi Üniversitesi Adresli: Evet
Özet
To investigate the level of nitric oxide (NO) in aqueous humour after excimer laser keratectomy in guinea pigs. Methods: NO levels of the aqueous humour were measured by nitric oxide analyser with chemiluminescence assay in three Groups. Group I served as control, 10 m$\mu$ excimer laser corneal photoablation was performed in Group II and 20 m$\mu$l corneal photoablation in Group III. Results: NO levels of all groups showed no difference when compared to the control (p>0.05). Conclusion: Excimer laser keratectomy did not change the NO level of aqueous humour in guinea pigs 24 hours following photoablation and this finding could be explained by increased transforming growth factor-$\beta$1, (TGF-$\beta$1) level of aqueous humour after excimer laser therapy.