Mu-opioid receptor binding measured by [C-11]carfentanil positron emission tomography is related to craving and mood in alcohol dependence

Bencherif, B; Wand, GS; McCaul, ME; Kim, YK; Iigin, NEŞE; Dannals, RF; Frost, JJ

doi:10.1016/j.biopsych.2003.07.007

Mu-opioid receptor binding measured by [C-11]carfentanil positron emission tomography is related to craving and mood in alcohol dependence

Bencherif B., Wand G., McCaul M., Kim Y., Iigin N., Dannals R., ...Daha Fazla

BIOLOGICAL PSYCHIATRY, cilt.55, sa.3, ss.255-262, 2004 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 55 Sayı: 3
Basım Tarihi: 2004
Doi Numarası: 10.1016/j.biopsych.2003.07.007
Dergi Adı: BIOLOGICAL PSYCHIATRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.255-262
Anahtar Kelimeler: Mu opioid receptors, alcoholism, craving, depression, PET imaging, COMPULSIVE DRINKING SCALE, BRAIN METABOLIC-CHANGES, FAMILY-HISTORY, ETHANOL-CONSUMPTION, BETA-ENDORPHIN, PSYCHOMETRIC PROPERTIES, NALTREXONE, RATS, NALOXONE, PREFERENCE
Gazi Üniversitesi Adresli: Evet

Özet

Background: The endogenous opioid system has been linked to alcohol dependence through animal and human studies. We investigated the relationship between alcohol craving and brain mu opioid receptors (R-OR) in alcohol-dependent subjects.