Mitomycin C prevents strictures in caustic esophageal burns in rats

Turkyilmaz Z., Sonmez K., Demirtola A., Karabulut R., Poyraz A., Gulen S., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.123, sa.2, ss.182-187, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 123 Sayı: 2
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1006/j.jss.2004.08.009
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.182-187
  • Anahtar Kelimeler: mitomycin C, caustic esophageal strictures, prevention, LYE STRICTURES, CORROSIVE ESOPHAGITIS, MORPHOLOGIC ASPECTS, CHILDREN, SURGERY, PENTOXIFYLLINE, INHIBITION, INJURIES, COLLAGEN, FIBROSIS
  • Gazi Üniversitesi Adresli: Evet

Özet

Background. Caustic esophageal. injuries lead to stricture formation. Although a number of agents have been tried experimentally to prevent strictures, few have gained clinical application. The purpose of this study was to investigate the effectiveness of Mitomycin C (MMC), which inhibits fibroblastic proliferation in preventing caustic esophageal strictures.