Mitomycin C prevents strictures in caustic esophageal burns in rats

Turkyilmaz, ZAFER; Sonmez, KAAN; Demirtola, A; Karabulut, RAMAZAN; Poyraz, A; Gulen, S; Dincer, SİBEL; Basaklar, AC; Kale, N

doi:10.1006/j.jss.2004.08.009

Mitomycin C prevents strictures in caustic esophageal burns in rats

Turkyilmaz Z., Sonmez K., Demirtola A., Karabulut R., Poyraz A., Gulen S., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.123, sa.2, ss.182-187, 2005 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 123 Sayı: 2
Basım Tarihi: 2005
Doi Numarası: 10.1006/j.jss.2004.08.009
Dergi Adı: JOURNAL OF SURGICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.182-187
Anahtar Kelimeler: mitomycin C, caustic esophageal strictures, prevention, LYE STRICTURES, CORROSIVE ESOPHAGITIS, MORPHOLOGIC ASPECTS, CHILDREN, SURGERY, PENTOXIFYLLINE, INHIBITION, INJURIES, COLLAGEN, FIBROSIS
Gazi Üniversitesi Adresli: Evet

Özet

Background. Caustic esophageal. injuries lead to stricture formation. Although a number of agents have been tried experimentally to prevent strictures, few have gained clinical application. The purpose of this study was to investigate the effectiveness of Mitomycin C (MMC), which inhibits fibroblastic proliferation in preventing caustic esophageal strictures.